The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Nov. 03, 2021
Applicants:

Interlude Biopharma Co., Miami, FL (US);

Oklahoma Medical Research Foundation, Oklahoma City, OK (US);

Inventors:

Jay P. Madan, Raleigh, NC (US);

Kathy L. Sivils, Oklahoma City, OK (US);

Umesh Deshmukh, Oklahoma City, OK (US);

Balasingham Radhakrishnan, Raleigh, NC (US);

Kendyle Kennsengten, Raleigh, NC (US);

Harini Bagavant, Oklahoma City, OK (US);

Assignees:

Interlude Biopharma Co., Miami, FL (US);

Oklahoma Medical Research Foundation, Oklahoma City, OK (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 31/196 (2006.01); A61K 31/606 (2006.01); A61K 38/08 (2019.01); A61P 1/02 (2006.01);
U.S. Cl.
CPC ...
A61K 38/08 (2013.01); A61K 31/196 (2013.01); A61K 31/606 (2013.01); A61P 1/02 (2018.01);
Abstract

The present invention provides compositions and methods for treating Sjogren's syndrome (SS), including primary or secondary SS, as well as methods for preventing clinical disease in patients at risk of developing clinical SS. In various embodiments, the invention relates to administering a regimen of larazotide (or derivative) and/or 4-APAA compounds or 5-ASA compounds (e.g., 5-ASA, 4-ASA, 4-Ac APAA, and 4-APAA) to a patient in need thereof.


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