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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12414969 B1

PDFFull Text
Date of Patent:
Sep. 16, 2025

Filed:

Oct. 17, 2022

Methods and compositions for reducing clostridium difficile infection

Applicant:

Memorial Sloan-kettering Cancer Center, New York, NY (US);

Inventors:

Eric Pamer, Guilford, CT (US);

Charlie Buffie, New York, NY (US);

Peter Mckenney, New York, NY (US);

Assignee:

Memorial Sloan-Kettering Cancer Center, New York, NY (US);

Attorney:

Baker Botts L.L.P.

Primary Examiner:

Oluwatosin A Ogunbiyi

Int. Cl.
CPC ...
A61K 35/74 (2015.01); A61K 38/44 (2006.01); A61K 45/06 (2006.01); C12N 9/00 (2006.01); C12N 9/04 (2006.01); C12Q 1/26 (2006.01);
U.S. Cl.
CPC ...
A61K 35/74 (2013.01); A61K 38/443 (2013.01); A61K 45/06 (2013.01); C12N 9/0006 (2013.01); C12Q 1/26 (2013.01); C12Y 101/01159 (2013.01);
Abstract

The present invention relates to methods and compositions for reducing the risk and severity ofinfection. It is based, at least in part, on the discovery that a restricted fraction of the gut microbiota, including the bacterium, contributes substantially to resistance againstinfection. Without being bound by any particular theory, it is believed that this is achieved through the biosynthesis of secondary bile acids.

Find Patent Forward Citations

Pamer, Eric. (2025). Methods and compositions for reducing clostridium difficile infection (U.S. Patent No. 12414969). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12414969

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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