The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Apr. 24, 2020
Applicant:

Children's Hospital Medical Center, Cincinnati, OH (US);

Inventors:

Takanori Takebe, Cincinnati, OH (US);

Rie Ouchi, Cincinnati, OH (US);

Assignee:

Children's Hospital Medical Center, Cincinnati, OH (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/407 (2015.01); A61K 9/00 (2006.01); A61K 31/575 (2006.01); A61K 45/06 (2006.01); A61P 1/16 (2006.01); C12N 5/071 (2010.01); C12N 5/074 (2010.01); C12N 15/01 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 35/407 (2013.01); A61K 9/0029 (2013.01); A61K 31/575 (2013.01); A61P 1/16 (2018.01); C12N 5/0671 (2013.01); C12N 5/0672 (2013.01); C12N 5/0696 (2013.01); C12N 5/0697 (2013.01); C12N 15/01 (2013.01); G01N 33/5008 (2013.01); A61K 45/06 (2013.01); C12N 2500/36 (2013.01); C12N 2501/119 (2013.01); C12N 2506/45 (2013.01);
Abstract

Disclosed are methods of treating or reducing the occurrence of a steatohepatitis disorder. The disorder may include, for example, NASH, parenteral nutrition associated liver disease (PNALD), or genetic forms of liver disease. The method may comprise the step of administering a composition comprising obeticholic acid to an individual in need thereof.


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