The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Jan. 18, 2023
Applicants:

Sichuan University, Chengdu, CN;

Nuclear Industry 416 Hospital, Chengdu, CN;

Inventors:

Shuyu Zhang, Chengdu, CN;

Fenghao Geng, Chengdu, CN;

Jianhui Chen, Chengdu, CN;

Xiaoqian Li, Chengdu, CN;

Assignees:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/517 (2006.01); A61P 17/02 (2006.01); A61P 17/16 (2006.01); A61P 17/18 (2006.01); A61P 29/00 (2006.01); A61P 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/517 (2013.01); A61P 17/02 (2018.01); A61P 17/16 (2018.01); A61P 17/18 (2018.01); A61P 29/00 (2018.01); A61P 39/00 (2018.01);
Abstract

The present disclosure relates to use of a compound in preparation of a medicament for prophylaxis and treatment of inflammatory tissue damage. The present disclosure provides use of a compound in preparation of a medicament for prophylaxis and treatment of tissue damage, and the compound has a structure represented by formula I. The compound having the structure represented by formula I provided by the present disclosure can inhibit transcriptional activity of interferon regulatory factor 1 (IRF1), have prophylactic and therapeutic effects on tissue damage, enhance cell proliferation ability after tissue cell injury, and repair injured tissues. The compound having the structure represented by formula I provided by the present disclosure has important significance and application value in the preparation of the medicament for prophylaxis and treatment of tissue damage, particularly in the preparation of a medicament for inflammatory injuries of skin tissues induced by radiation and/or oxidation.


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