The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
May. 08, 2024
Barry P. Rosen, Boynton Beach, FL (US);
Kunie Yoshinaga-sakurai, Miami, FL (US);
Venkadesh Sarkarai Nadar, Miami, FL (US);
Barry P. Rosen, Boynton Beach, FL (US);
Kunie Yoshinaga-Sakurai, Miami, FL (US);
Venkadesh Sarkarai Nadar, Miami, FL (US);
The Florida International University Board of Trustees, Miami, FL (US);
Abstract
The subject invention provides organoarsenicals or salts thereof, compositions comprising an organoarsenical or a salt thereof, and methods of using the organoarsenicals or salts thereof, or compositions for inhibiting glutaminase and for treating cancers. Specifically, the subject invention provides methods of inhibiting glutaminase (e.g., KGA) catalytic activity in a cell, methods of treating cancer or a tumor via, for example, the inhibition of glutaminase activity, and methods of disrupting and/or inhibiting growth and proliferation of cancerous or tumorous cells.