The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Aug. 17, 2017
Applicant:
Shanghai Jiao Tong University, Shanghai, CN;
Inventors:
Assignee:
SHANGHAI JIAO TONG UNIVERSITY, Shanghai, CN;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/203 (2006.01); A61K 9/1272 (2025.01); A61K 9/1278 (2025.01); A61K 47/10 (2017.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01); A61K 47/40 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/203 (2013.01); A61K 9/1272 (2013.01); A61K 9/1278 (2013.01); A61K 47/10 (2013.01); A61K 47/32 (2013.01); A61K 47/38 (2013.01); A61K 47/40 (2013.01); A61P 35/00 (2018.01);
Abstract
The present disclosure relates to an all-trans retinoic acid liposome formulation and a preparation method thereof. The all-trans retinoic acid liposome formulation includes all-trans retinoic acid and a liposome vector. The disclosure adopts an active drug loading method, including a calcium acetate gradient method or a sodium acetate gradient method. The prepared all-trans retinoic acid formulation has high drug loading and high stability in vivo, thereby increasing the blood concentration and prolonging the half-life of the all-trans retinoic acid.