The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 16, 2025

Filed:

Aug. 02, 2024
Applicants:

Neuronasal, Inc., Wexford, PA (US);

Burke Neurological Institute, White Plains, NY (US);

Inventors:

Douglas A. Greene, Basking Ridge, NJ (US);

Rajiv R. Ratan, White Plains, NY (US);

Thomas I. Bradshaw, Wynnewood, PA (US);

Assignees:

Neuronasal, Inc., Wexford, PA (US);

Burke Neurological Institute, White Plains, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 9/0043 (2013.01); A61K 9/0075 (2013.01); A61K 9/0078 (2013.01);
Abstract

The present disclosure describes methods of administering N-acetylcysteine (NAC) via intranasal nose-to-brain administration. The effect of intranasal NAC nose-to-brain administration can be monitored using an analytical technique, for example, magnetic resonance spectroscopy (MRS). In some embodiments, intranasal nose-to-brain NAC can be used to treat a condition, for example, a brain injury.


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