The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 16, 2025
Filed:
Jul. 02, 2020
Applicant:
Innovation Ulster Limited, Antrim, GB;
Inventors:
Assignee:
INNOVATION ULSTER LIMITED, Antrim, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 9/51 (2006.01); A61K 31/352 (2006.01); A61K 31/403 (2006.01); A61K 31/4745 (2006.01); A61K 41/00 (2020.01); A61P 1/18 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5146 (2013.01); A61K 9/5153 (2013.01); A61K 31/352 (2013.01); A61K 31/403 (2013.01); A61K 31/4745 (2013.01); A61K 41/0033 (2013.01); A61K 49/0054 (2013.01); A61P 1/18 (2018.01); A61P 35/00 (2018.01); A61P 35/04 (2018.01);
Abstract
The invention provides polymeric particles comprising a matrix of a biocompatible polymer and polyethylene imine, said matrix having incorporated therein an anionic or hydrophobic sonosensitiser and, optionally, an immunomodulatory agent and/or an imaging agent. Such particles find use in methods of sonodynamic therapy, in particular in methods of combined sonodynamic therapy and immunotherapy, for example in the treatment of cancer, metastasis or micrometastasis derived from cancer. The invention is particularly suitable for the treatment of deep-sited, hard to treat tumours such as pancreatic cancer.