The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Dec. 01, 2021
Ecole Polytechnique Federale DE Lausanne (Epfl), Lausanne, CH;
Mihai Adrian Ionescu, Ecublens, CH;
Sheibani Shokoofeh, St-Sulpice, CH;
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), Lausanne, CH;
Abstract
One embodiment of the present invention concerns a biosensor for sensing stress hormone cortisol concentration in a biofluid. The biosensor comprises: an electrical transistor transducer comprising a transistor gate electrode; a sensing electrode element comprising a metal element having a biofluid facing surface, and a graphene layer on the biofluid facing surface of the metal element, the sensing electrode element being connected to the transistor gate electrode by an electrical connector to form an extended gate configuration with the transistor gate electrode; and a reference electrode configured to be in contact with the biofluid, and configured to electrically bias the transistor gate electrode through the biofluid. The sensing electrode element is functionalised by at least a layer of aptamers placed indirectly or directly on the graphene layer, and configured to catch cortisol hormones in the biofluid to thereby change a surface potential of the sensing electrode element.