The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Mar. 22, 2022
Applicant:
American Gene Technologies International Inc., Rockville, MD (US);
Inventors:
Tyler Lahusen, Rockville, MD (US);
Lingzhi Xiao, Rockville, MD (US);
Charles David Pauza, Rockville, MD (US);
Assignee:
American Gene Technologies International Inc., Rockville, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/86 (2013.01); C12N 15/113 (2013.01); C12N 2310/14 (2013.01); C12N 2740/15023 (2013.01); C12N 2740/15043 (2013.01);
Abstract
Viral vectors, lentiviral particles, and modified cells are disclosed. They encode or express a small RNA capable of targeting the KIF11 gene. In embodiments, the viral vectors and lentiviral particles further comprise and a KIF11 gene whose non-coding region has been modified such that it is resistant to activity by the small RNA.