The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Jun. 08, 2022
Applicant:
Wisconsin Alumni Research Foundation (Warf), Madison, WI (US);
Inventors:
Yoshihiro Kawaoka, Middleton, WI (US);
Gabriele Neumann, Madison, WI (US);
Makoto Ozawa, Kagoshima, JP;
Assignee:
Wisconsin Alumni Research Foundation (WARF), Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/00 (2006.01); A61K 35/76 (2015.01); A61K 39/09 (2006.01); A61K 39/12 (2006.01); A61K 39/145 (2006.01); G01N 33/569 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/00 (2013.01); A61K 35/76 (2013.01); A61K 39/092 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); G01N 33/56983 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5254 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/543 (2013.01); A61K 2039/70 (2013.01); C12N 2760/16121 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16143 (2013.01); C12N 2760/16151 (2013.01); C12N 2760/16171 (2013.01); G01N 2333/11 (2013.01);
Abstract
The invention provides a recombinant biologically contained influenza virus that is a PB2 knockout virus, e.g., one that is useful to generate a multivalent vaccine, and methods of making and using that virus.