The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Jun. 05, 2020
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Igor I. Slukvin, Verona, WI (US);
Vera Sergeyevna Brok Volchanskaya, Singapore, SG;
Kran Suknuntha, Madison, WI (US);
Anna Huttenlocher, Madison, WI (US);
David Alfred Bennin, Mount Horeb, WI (US);
Lucas Klemm, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation (WARF), Madison, WI (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0783 (2010.01); A61K 40/10 (2025.01); A61K 40/42 (2025.01); A61K 40/45 (2025.01); C12N 5/0786 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0636 (2013.01); A61K 40/10 (2025.01); A61K 40/4242 (2025.01); A61K 40/4544 (2025.01); C12N 5/0645 (2013.01); C12N 2500/02 (2013.01); C12N 2501/113 (2013.01); C12N 2501/155 (2013.01); C12N 2501/165 (2013.01); C12N 2501/23 (2013.01); C12N 2501/26 (2013.01); C12N 2501/599 (2013.01); C12N 2506/45 (2013.01);
Abstract
The present invention provides methods of producing in vitro derived neutrophils or macrophages in xenogen- and serum-free conditions from pluripotent stem cells and in vitro derived populations of neutrophils and macrophages. Methods of treatment using in vitro derived neutrophils or macrophages are also contemplated.