The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Sep. 11, 2023
Applicant:

University of Maryland, Baltimore County, Baltimore, MD (US);

Inventors:

Govind Rao, Ellicott City, MD (US);

Yordan Kostov, Columbia, MD (US);

Abhay Andar, Gaithersburg, MD (US);

Mustafa Al-Adhami, Silver Spring, MD (US);

Sevda Deldari, Baltimore, MD (US);

Douglas D. Frey, Baltimore, MD (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); A61K 38/00 (2006.01); C12M 1/00 (2006.01); C12M 1/02 (2006.01); C12M 1/26 (2006.01); C12M 1/34 (2006.01); C12M 3/00 (2006.01); C12M 3/06 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); A61K 38/00 (2013.01); C12M 23/44 (2013.01); C12M 27/00 (2013.01); C12M 29/20 (2013.01); C12M 33/14 (2013.01); C12M 41/12 (2013.01); C12M 41/26 (2013.01); C12M 41/28 (2013.01); C12M 41/40 (2013.01);
Abstract

The present invention provides for a fully integrated microfluidic system capable of producing single-dose amounts of biotherapeutics at the point-of-care wherein protein production, purification and product harvest are all integrated as a single microfluidic device which is portable and capable of continuous-flow production of biotherapeutics at the microscale using a cell-free reaction system.


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