The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Sep. 13, 2023
Applicant:

Ngm Biopharmaceuticals, Inc., South San Francisco, CA (US);

Inventors:

Dana Yen Mei Duey, San Francisco, CA (US);

Allen James Ebens, Jr., San Carlos, CA (US);

Daniel David Kaplan, San Mateo, CA (US);

Chia-Ying Kao Lam, South San Francisco, CA (US);

Kalyani Mondal, San Mateo, CA (US);

Geoffrey William Stone, San Francisco, CA (US);

Yan Wang, Foster City, CA (US);

Assignee:

NGM Biopharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

The present disclosure provides binding agents, such as antibodies, that specifically bind ILT2, ILT4, or both ILT2 and ILT4, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising the binding agents.


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