The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Jan. 05, 2022
Applicant:
Cephalon Llc, West Chester, PA (US);
Inventors:
David Jose Simon Laine, Macquarie Park, AU;
Matthew Pollard, Pullenvale, AU;
Anthony Gerard Doyle, Macquarie Park, AU;
Lynn Dorothy Poulton, Macquarie Park, AU;
Adam William Clarke, Macquarie Park, AU;
Assignee:
Cephalon LLC, West Chester, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/09 (2006.01); A61P 1/00 (2006.01); A61P 3/00 (2006.01); A61P 29/02 (2006.01); A61P 37/00 (2006.01); C07K 16/24 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/244 (2013.01); A61P 1/00 (2018.01); A61P 3/00 (2018.01); A61P 29/02 (2018.01); A61P 37/00 (2018.01); A61K 2039/505 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract
Recombinant antibodies that specifically bind to IL-15 as well as a complex of IL-15 and the IL-15 Receptor-alpha are provided. The antibodies inhibit immune cell proliferation, and are capable of use in the treatment of any autoimmune or inflammatory disease or condition where IL-15 is dysregulated, including Celiac disease.