The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Jun. 19, 2020
Applicant:
Icahn School of Medicine AT Mount Sinai, New York, NY (US);
Inventors:
Thomas Moran, New York, NY (US);
Thomas Kraus, New York, NY (US);
J. Andrew Duty, New York, NY (US);
Domenico Tortorella, New York, NY (US);
Assignee:
ICAHN School of Medicine at Mount Sinai, New York, NY (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); A61P 25/28 (2006.01); A61P 31/20 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C07K 16/08 (2013.01); C12N 15/63 (2013.01); A61P 25/28 (2018.01); A61P 31/20 (2018.01); C07K 16/084 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/76 (2013.01);
Abstract
Provided herein are monoclonal antibodies and antigen-binding fragments thereof that bind to the John Cunningham virus. Also provided are pharmaceutical compositions comprising the monoclonal antibodies and antigen-binding fragments thereof, as well as methods of using such monoclonal antibodies and antigen-binding fragments thereof, including methods for the treatment and/or prevention of JCV infections and/or progressive multifocal leukoencephalopathy.