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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12410183 B1

PDFFull Text
Date of Patent:
Sep. 09, 2025

Filed:

Jun. 14, 2024

Sars-cov2 main protease inhibitors

Applicant:

Gilead Sciences, Inc., Foster City, CA (US);

Inventors:

Stephen E. Ammann, Foster City, CA (US);

Xinpei Cai, San Mateo, CA (US);

Eda Y. Canales, San Mateo, CA (US);

Weng K. Chang, San Lorenzo, CA (US);

Gregory F. Chin, San Francisco, CA (US);

Henok H. Kinfe, Foster City, CA (US);

Scott E. Lazerwith, San Francisco, CA (US);

Jessica L Mckinley, Foster City, CA (US);

Michael R. Mish, Foster City, CA (US);

Devan Naduthambi, San Bruno, CA (US);

Jason K. Perry, San Francisco, CA (US);

Kevin X Rodriguez, San Mateo, CA (US);

Scott D. Schroeder, Union City, CA (US);

Christopher J. Swank, San Mateo, CA (US);

Joshua J. Van Veldhuizen, Seattle, WA (US);

Assignee:

Gilead Sciences, Inc., Foster City, CA (US);

Attorney:

Fish & Richardson P.C.

Primary Examiner:

Kristin A Vajda

Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61P 31/14 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 487/10 (2006.01); C07D 491/107 (2006.01); C07D 491/113 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61P 31/14 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 487/10 (2013.01); C07D 491/107 (2013.01); C07D 491/113 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present disclosure relates to compounds of Formula I: and pharmaceutically acceptable salts thereof, pharmaceutical compositions thereof, useful in the treatment of treating viral infections, for example, coronaviridae infections.

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