The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Sep. 03, 2020
Applicant:
Intra-cellular Therapies, Inc., New York, NY (US);
Inventors:
Peng Li, New Milford, NJ (US);
Robert Davis, San Diego, CA (US);
Assignee:
INTRA-CELLULAR THERAPIES, INC., Bedminster, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/14 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/14 (2013.01); A61K 38/005 (2013.01);
Abstract
The present invention relates to PDE1 inhibitory compounds useful in the treatment of diseases involving disorders of the dopamine D1 receptor intracellular pathway, such as, among others, Parkinson's disease, depression, narcolepsy, psychosis, damage to cognitive function, e.g., in schizophrenia, or disorders that may be ameliorated through enhanced progesterone-signaling pathway, as well as their use as pharmaceuticals and pharmaceutical compositions comprising them. Methods of making and methods of use related to such compounds are further described.