The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Jun. 03, 2020
Applicant:

Arcus Biosciences, Inc., Hayward, CA (US);

Inventors:

Joel Worley Beatty, San Mateo, CA (US);

Samuel Lawrie Drew, Millbrae, CA (US);

Jeremy Thomas Andre Fournier, Fremont, CA (US);

Jenna Leigh Jeffrey, Oakland, CA (US);

Kenneth Victor Lawson, San Francisco, CA (US);

Manmohan Reddy Leleti, Dublin, CA (US);

Artur Karenovich Mailyan, Hayward, CA (US);

Guillaume Mata, Berkeley, CA (US);

Dillon Harding Miles, Berkeley, CA (US);

Jay Patrick Powers, Pacifica, CA (US);

Ehesan Ui Sharif, Menlo Park, CA (US);

Rhiannon Thomas-Tran, San Jose, CA (US);

Xuelei Yan, Foster City, CA (US);

Assignee:

Arcus Biosciences, Inc., Hayward, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 45/06 (2006.01); A61N 5/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 45/06 (2013.01); A61N 5/06 (2013.01); A61N 2005/0636 (2013.01);
Abstract

Compounds that inhibit PI3Kγ, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by PI3Kγ.


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