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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12410168 B1

PDFFull Text
Date of Patent:
Sep. 09, 2025

Filed:

Feb. 22, 2024

Pyrazolopyridine derivative having glp-1 receptor agonist effect

Applicant:

Chugai Seiyaku Kabushiki Kaisha, Tokyo, JP;

Inventors:

Hitoshi Yoshino, Shizuoka, JP;

Satoshi Tsuchiya, Shizuoka, JP;

Atsushi Matsuo, Shizuoka, JP;

Tsutomu Sato, Shizuoka, JP;

Masahiro Nishimoto, Shizuoka, JP;

Kyoko Oguri, Shizuoka, JP;

Hiroko Ogawa, Shizuoka, JP;

Yoshikazu Nishimura, Shizuoka, JP;

Yoshiyuki Furuta, Kanagawa, JP;

Hirotaka Kashiwagi, Shizuoka, JP;

Nobuyuki Hori, Shizuoka, JP;

Takuma Kamon, Shizuoka, JP;

Takuya Shiraishi, Shizuoka, JP;

Shoshin Yoshida, Shizuoka, JP;

Takahiro Kawai, Shizuoka, JP;

Satoshi Tanida, Shizuoka, JP;

Masahide Aoki, Shizuoka, JP;

Assignee:

CHUGAI SEIYAKU KABUSHIKI KAISHA, Tokyo, JP;

Attorney:

Yong Zhao

Primary Examiner:

Brenda L Coleman

Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/437 (2006.01); A61K 31/444 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/496 (2006.01); A61K 31/506 (2006.01); A61K 31/5377 (2006.01); A61K 31/5386 (2006.01); A61P 1/16 (2006.01); A61P 3/04 (2006.01); A61P 3/06 (2006.01); A61P 3/10 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 25/16 (2006.01); A61P 25/28 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4709 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/506 (2013.01); A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61P 1/16 (2018.01); A61P 3/04 (2018.01); A61P 3/06 (2018.01); A61P 3/10 (2018.01); A61P 9/10 (2018.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01); C07D 519/00 (2013.01);
Abstract

The present invention provides a compound having the basic structure shown by Formula (I) in which the indole ring and the pyrazolopyridine structure is bound through a substituent, a salt thereof or a solvate of either the compound or a salt of the compound, as well as a preventative agent or a therapeutic agent for non-insulin-dependent diabetes mellitus (Type 2 diabetes) or obesity containing such compound, salt or solvate as an active ingredient.

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