The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
Mar. 21, 2024
Applicant:
Acuitas Therapeutics, Inc., Vancouver, CA;
Inventors:
Julia Gatenyo, Vancouver, CA;
Xinyao Du, Richmond, CA;
Assignee:
Acuitas Therapeutics, Inc., Vancouver, CA;
Primary Examiner:
Int. Cl.
CPC ...
C07C 219/06 (2006.01); A61K 9/51 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07C 219/06 (2013.01); A61K 9/5123 (2013.01); A61K 39/12 (2013.01); A61K 2039/55555 (2013.01);
Abstract
Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, wherein a, b, c, d, G, G, L, L, R, R, R, R, R, R, R, R, R, R, R, Rand X are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, nanoparticles comprising the compounds and methods for their use and preparation are also provided.