The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Jul. 27, 2020
Applicant:

The University of Tokyo, Tokyo, JP;

Inventors:

Kanjiro Miyata, Tokyo, JP;

Beob Soo Kim, Tokyo, JP;

Shigehito Osawa, Tokyo, JP;

Mitsuru Naito, Tokyo, JP;

Hiroyuki Chaya, Tokyo, JP;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/61 (2017.01); A61K 9/107 (2006.01); A61K 47/54 (2017.01); A61K 47/55 (2017.01);
U.S. Cl.
CPC ...
A61K 47/61 (2017.08); A61K 9/1075 (2013.01); A61K 47/545 (2017.08); A61K 47/55 (2017.08);
Abstract

A drug-polymer conjugate having thermoresponsiveness includes at least one drug conjugated to at least one end portion of at least one thermoresponsive polymer segment having a lower critical solution temperature. The drug-polymer conjugate is capable of forming a micellular aggregate in an aqueous medium at temperatures equal to or above the lower critical solution temperature. The drug-polymer conjugate or the micellular aggregate thereof may be administered to and absorbed in the lungs.


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