The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2025
Filed:
May. 13, 2020
Applicant:
Hadasit Medical Research Services & Development Ltd., Jerusalem, IL;
Inventors:
Shimon Reif, Jerusalem, IL;
Regina Golan-Gerstl, Maale Michmash, IL;
Assignee:
HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD., Jerusalem, IL;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 36/00 (2006.01); A61K 9/00 (2006.01); A61K 9/127 (2006.01); A61K 31/7105 (2006.01); A61K 35/20 (2006.01); A61K 38/18 (2006.01); A61P 1/12 (2006.01);
U.S. Cl.
CPC ...
A61K 35/20 (2013.01); A61K 9/0053 (2013.01); A61K 9/127 (2013.01); A61K 31/7105 (2013.01); A61K 38/1841 (2013.01); A61P 1/12 (2018.01);
Abstract
The present invention is directed to compositions containing exosomes isolated from milk and methods and uses thereof for treating inflammatory bowel disease (IBD) and conditions related thereto. In particular, disclosed are exosomes derived from milk and enteral formulations supplemented therewith for use in treating IBD. The compositions are preferably formulated for rectal administration and the exosomes comprise one or more miRNA molecules and TGF-β.