The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Aug. 24, 2020
Applicant:

Flagship Pioneering Innovations Vi, Llc, Cambridge, MA (US);

Inventors:

Maria Helena Christine Van Rooijen, Cambridge, MA (US);

Hok Hei Tam, Newton, MA (US);

Maier Steve Avendaño Amado, Cambridge, MA (US);

Barry Andrew Martin, Boston, MA (US);

Ignacio Martinez, Lexington, MA (US);

Piotr Stanislaw Kowalski, Cork, IE;

Nataliya Vladimirovna Nukolova, Cambridge, MA (US);

John Patrick Casey, Jr., Boston, MA (US);

Siddharth Dilipkumar Patel, Cambridge, MA (US);

Roman Lvovitch Bogorad, Newton, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/1272 (2025.01); A61K 47/60 (2017.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1272 (2013.01); A61K 47/60 (2017.08); C12N 15/88 (2013.01);
Abstract

Disclosed herein are compositions including a plurality of plant messenger packs, (e.g., including a plant extracellular vesicle (EV), or segment, portion, or extract thereof), that are modified to have enhanced cell uptake (e.g., animal plant cell uptake, bacterial cell uptake, or fungal cell uptake), e.g., for use in a variety of agricultural or therapeutic methods.


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