The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 09, 2025

Filed:

Dec. 16, 2022
Applicant:

The General Hospital Corporation, Boston, MA (US);

Inventors:

Rajiv Gupta, Wayland, MA (US);

Chika Kamezawa, Boston, MA (US);

Avilash Cramer, Cambridge, MA (US);

Wolfgang Krull, Boxford, MA (US);

Wataru Yashiro, Boston, MA (US);

Kazuyuki Hyodo, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 6/00 (2024.01); A61B 6/46 (2024.01);
U.S. Cl.
CPC ...
A61B 6/486 (2013.01); A61B 6/461 (2013.01); A61B 6/5217 (2013.01); A61B 6/5258 (2013.01); A61B 6/542 (2013.01);
Abstract

X-ray absorption of breast cancers and surrounding healthy tissue can be very similar, a situation that sometimes leads to missed cancers or false-positive diagnoses. To increase the accuracy of tomosynthesis and cancer diagnosis, dynamic X-ray elastography using a novel pulsed X-ray source synchronized to shear waves generated in a sample is described in the present disclosure. This imaging modality provides both absorption and mechanical properties of the imaged sample. A vibration source is used to vibrate the sample while a synchronously pulsed cold cathode X-ray source images the mechanical deformation. The generated stroboscopic images are further used to derive stiffness maps of the sample in addition to the conventional X-ray image.


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