The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Feb. 18, 2022
Applicant:
Dionex Corporation, Sunnyvale, CA (US);
Assignee:
Dionex Corporation, Sunnyvale, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/72 (2006.01); G01N 30/16 (2006.01); G01N 30/30 (2006.01); G01N 30/32 (2006.01); G01N 30/64 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/7266 (2013.01); G01N 30/16 (2013.01); G01N 30/30 (2013.01); G01N 30/32 (2013.01); G01N 30/64 (2013.01); G01N 2030/027 (2013.01); G01N 2030/326 (2013.01);
Abstract
A novel analytical system and method to analyze complex carbohydrates such as human milk oligosaccharides by low-temperature High-Performance Anion Exchange Chromatography with Pulsed Amperometric Detection and High-resolution Mass Spectrometry (HPAE-PAD-MS). The analytical system controls the temperature of the column, electrochemical detector, and ion removal device at or below 15° C. The HPAE-PAD workflow with high-resolution mass spectrometry provides useful molecular structure information. It facilitates the detection of milk oligosaccharides, particularly unknown structures, without the use of analytical standards.