The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Nov. 02, 2022
Applicant:

Gnothis Holding Ag, Cham, CH;

Inventor:

Rudolf Rigler, Djursholm, SE;

Assignee:

GNOTHIS HOLDING AG, Cham, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); B01L 3/00 (2006.01); G01N 1/40 (2006.01); G01N 21/64 (2006.01); G01N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); B01L 3/5085 (2013.01); G01N 1/40 (2013.01); G01N 21/6428 (2013.01); G01N 21/648 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0819 (2013.01); G01N 2001/4038 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/1028 (2024.01); G01N 21/6408 (2013.01); G01N 2021/6439 (2013.01);
Abstract

The invention relates to a process and a device for analyzing single molecules, particularly to the parallel analysis of a plurality of single molecules. It is suitable for detecting interactions, e.g. binding between single molecules and/or reactions, e.g. elongation or degradation of single molecules. Particularly, the process of the invention relates to the sequencing of single nucleic acid molecules. The single molecule to be analyzed is present in free form, i.e. dissolved or suspended in a liquid medium, within a reaction space formed around the sample spot. According to the present invention, an electrical field is applied across the reaction space, whereby a concentration of single molecules, at the sample spots is effected.


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