The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Sep. 13, 2024
Applicant:

Diagenode S.a., Seraing, BE;

Inventors:

Clément Cassart, Vaux-et-Borset, BE;

Renaud Schoemans, Seraing, BE;

Assignee:

Diagenode S.A., Ougree, BE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6851 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6851 (2013.01);
Abstract

The invention provides methods for quantitative analysis of methylation content of a test sample. The method employs an internal control within the same test sample and an external control within a reference sample to reduce sources of random variability. The internal control corrects for variability arising from conducting separate amplifications as occurs in an external control, and the external control corrects for variability between amplification at different loci as occurs with the internal control. The steps for processing and analyzing the test sample can occur in a single reaction vessel facilitating automation of the assay. Information regarding methylation content generated by the methods can be used in diagnosing and treatment of disorders and for forensic purposes among other applications.


Find Patent Forward Citations

Cassart, Clément. (2025). Detection of methylation status of a dna sample (U.S. Patent No. 12404546). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12404546

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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