The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Jan. 10, 2020
Northwestern University, Evanston, IL (US);
Cornell University, Ithaca, NY (US);
Michael Christopher Jewett, Evanston, IL (US);
Jessica Carol Stark, Evanston, IL (US);
Matthew P. Delisa, Ithaca, NY (US);
Thapakorn Jaroentomeechai, Ithaca, NY (US);
Northwestern University, Evanston, IL (US);
Cornell University, Ithaca, NY (US);
Abstract
Disclosed are methods, systems, components, and compositions for cell-free synthesis of glycosylated proteins, which may be utilized in vaccines, including anti-bacterial vaccines. The glycosylated proteins may include a bacterial polysaccharide conjugated to a carrier, which may be utilized to generate an immune response in an immunized host against the polysaccharide conjugated to the carrier. Suitable carriers may include but are not limited toprotein D (PD),porin protein (PorA),toxin (CRM 197),toxin (TT), andmaltose binding protein, and variants thereof.