The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Apr. 10, 2024
Applicant:

Viridos, Inc., La Jolla, CA (US);

Inventors:

Saheed Imam, La Jolla, CA (US);

Eric R. Moellering, La Jolla, CA (US);

Luke Peach, La Jolla, CA (US);

Wiilliam F. Lambert, La Jolla, CA (US);

Kathleen Kwok, La Jolla, CA (US);

Assignee:

Viridos, Inc., La Jolla, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 7/64 (2022.01); C07K 14/405 (2006.01); C12N 1/12 (2006.01);
U.S. Cl.
CPC ...
C12P 7/64 (2013.01); C07K 14/405 (2013.01); C12N 1/125 (2021.05);
Abstract

The invention provides recombinant algal mutants that have a genetic modification to a gene or nucleic acid sequence encoding a WD40 repeat containing protein or domain. The genetic modification of one or more nucleic acid sequences encoding a WD40 repeat containing protein or domain results in a mutant organism with increased lipid productivity and/or higher biomass productivity (as measured by total organic carbon). The genetic modification can be a gene attenuation or functional deletion. The lipid products of these mutants can be utilized as biofuels or for other specialty chemical products. Methods of making and using the recombinant algal mutants and methods of producing lipids are also disclosed.


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