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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12404349 B1

PDFFull Text
Date of Patent:
Sep. 02, 2025

Filed:

Oct. 03, 2023

Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers

Applicant:

Navidea Biopharmaceuticals, Inc., Columbus, OH (US);

Inventors:

Jeffrey Scott Arnold, Andover, MA (US);

David A. Ralph, Columbus, OH (US);

Assignee:

Navidea Biopharmaceuticals, Inc., Columbus, OH (US);

Attorney:

Fredrikson & Byron, P.A.

Primary Examiner:

Jonathan S Lau

Int. Cl.
CPC ...
C08B 37/02 (2006.01); A61K 31/717 (2006.01); A61K 31/721 (2006.01); A61K 31/722 (2006.01); A61K 31/728 (2006.01); C08B 37/00 (2006.01); C08B 37/08 (2006.01);
U.S. Cl.
CPC ...
C08B 37/0021 (2013.01); A61K 31/717 (2013.01); A61K 31/721 (2013.01); A61K 31/722 (2013.01); A61K 31/728 (2013.01); C08B 37/003 (2013.01); C08B 37/0072 (2013.01); C08B 37/0087 (2013.01);
Abstract

Provided are methods of attaching a mannose-binding C-type lectin receptor targeting moiety to a polymeric carbohydrate backbone using an amide linkage. The amide linkage may be found between a leash, such as an amine terminated leash, and the mannose-binding C-type lectin receptor targeting moieties. The compounds and compositions disclosed utilizing the amide linkage provide for highly stable compounds with a significant reduction in loss of mannose-binding C-type lectin receptor targeting moieties from the polymeric carbohydrate backbone.

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Arnold, Jeffrey. (2025). Amide linkages of sugar moieties to amine terminated leashes attached to carbohydrate polymers (U.S. Patent No. 12404349). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12404349

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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