The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Nov. 18, 2022
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Amit Choudhary, Boston, MA (US);
Vika Anokhina, Cambridge, MA (US);
Santosh Chaudhary, Cambridge, MA (US);
Prashant Singh, Cambridge, MA (US);
Sameek Singh, Cambridge, MA (US);
Veronika Shoba, Cambridge, MA (US);
Uttam Dhawa, Cambridge, MA (US);
Ashley Modell, Cambridge, MA (US);
Praveen Tiwari, Boston, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
The Broad Institute, Inc., Cambridge, MA (US);
Abstract
The present disclosure relates to chimeric small molecules, which find utility as modifiers of target substrates according to the formula A-L-E-B or A-L-E-L-B, wherein A is a kinase binding moiety; B is a target binding moiety; Land Lare each a linker; and E is an electrophilic reactive group. Molecules according to the present invention find use making substrate modifications such as post-translational modifications to targets that are not the natural substrate of the kinase; accordingly, diseases or disorders may be treated or prevented with molecules of the present disclosure.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile