The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Mar. 03, 2022
Applicant:

The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);

Inventors:

Frank J. Rauscher, Wayne, PA (US);

Peter Mondics, Newtown Square, PA (US);

Assignees:

The Wistar Institute of Anatomy and Biology, Philadelphia, PA (US);

Innate Biologics LLC, Harrisburg, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/255 (2006.01); A61K 38/00 (2006.01); C07K 14/25 (2006.01);
U.S. Cl.
CPC ...
C07K 14/255 (2013.01); C07K 14/25 (2013.01); A61K 38/00 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01); C07K 2319/70 (2013.01);
Abstract

Provided herein are methods and compositions comprising a set of paired peptides comprising a first bacterial effector polypeptide or fragment thereof linked to a second bacterial effector polypeptide or fragment thereof. The paired peptides can be linked to a protein transduction domain. The compositions can be formulated as pharmaceuticals. The compositions are useful for the treatment of inflammatory disorders.


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