The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Dec. 20, 2022
Applicant:
Kite Pharma, Inc., Santa Monica, CA (US);
Inventors:
Stuart A. Sievers, Van Nuys, CA (US);
Jed J. W. Wiltzius, Winchester, MA (US);
Assignee:
Kite Pharma, Inc., Santa Monica, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/42 (2025.01); A61K 47/65 (2017.01); A61P 35/02 (2006.01); C07K 4/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C07K 16/28 (2006.01); C07K 16/44 (2006.01); C12N 15/62 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
C07K 14/003 (2013.01); A61K 40/11 (2025.01); A61K 40/31 (2025.01); A61K 40/4211 (2025.01); A61K 47/65 (2017.08); A61P 35/02 (2018.01); C07K 4/00 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C07K 16/2803 (2013.01); C07K 16/44 (2013.01); C12N 15/62 (2013.01); C12N 15/85 (2013.01); C07K 2317/32 (2013.01); C07K 2317/34 (2013.01); C07K 2317/622 (2013.01); C07K 2319/40 (2013.01);
Abstract
The invention provides novel peptides (e.g., linkers) and polypeptide compositions comprising the linkers (e.g., fusion proteins) and methods of using the polypeptide compositions. Peptides (e.g., linkers) are useful as tags and for engineering fusion proteins (e.g., antigen binding molecules, scFv). Polypeptide linkers described herein facilitate flexibility of linked peptides allowing for proper folding, conformation and reduced immunogenicity.