The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
May. 20, 2020
Sierra Sciences, Llc, Reno, NV (US);
William H. Andrews, Reno, NV (US);
Christopher A. Foster, Carmichael, CA (US);
Lancer K. Brown, Sparks, NV (US);
Laura A. Briggs, Reno, NV (US);
October Pawlik, Sparks, NV (US);
Penelope Burke, Reno, NV (US);
Federico C. A. Gaeta, Mountain View, CA (US);
Beril Karakas, Reno, NV (US);
Jessica Wheeler, Sparks, NV (US);
Mieczyslaw A. Piatyszek, Morgan Hill, CA (US);
Munirathnam Chaguturu, Lawrence, KS (US);
Jian Zhang, Fremont, CA (US);
Tom Kerley, Gardnerville, NV (US);
Hamid Mohammadpour, Reno, NV (US);
Sierra Sciences, LLC, Reno, NV (US);
Abstract
Telomerase reverse transcriptase (TERT) expression enhancing compounds, and methods for using the same, are provided. In some embodiments, the compounds are azoles, such as such as pyrazoles, imidazoles, triazoles, tetrazoles, thiazoles, isothiazoles, oxazoles, and isoxazoles. In certain embodiments, the azole compound includes an acyl substituent which includes an amide, for example, an alkyl amide. Methods of interest include contacting cells with a TERT expression enhancing effective amount of compound to increase TERT expression in the cells. These compounds and methods find use in a variety of applications in which increased expression of telomerase reverse transcriptase is desired.