The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Nov. 21, 2023
Incyte Corporation, Wilmington, DE (US);
Dengjin Wang, Wilmington, DE (US);
Daniel Carper, Wilmington, DE (US);
Zhongjiang Jia, Kennett Square, PA (US);
Bo Shen, Garnet Valley, PA (US);
Joseph A. Sclafani, Malvern, PA (US);
Robert Wilson, Wilmington, DE (US);
Jiacheng Zhou, Newark, DE (US);
Osama Suleiman, Cambridge, GB;
Mark Wright, Cambridge, GB;
Incyte Corporation, Wilmington, DE (US);
Abstract
This application relates to processes and intermediates for the preparation of the PD-1/PD-L1 inhibitor (R)-1-((7-cyano-2-(3'-((2-(difluoromethyl)-7-((3-hydroxypyrrolidin-1-yl)methyl)pyrido[3,2-d]pyrimidin-4-yl)amino)-2,2′-dimethyl-[1,1′-biphenyl]-3-yl)benzo[d]oxazol-5-yl)methyl)piperidine-4-carboxylic acid, and salts and crystalline forms thereof, where the PD-1/PD-L1 inhibitor and solid forms and salt forms thereof are useful in the treatment of various diseases including infectious diseases and cancer.