The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Jul. 24, 2024
Applicant:
Astrazeneca Ab, Sodertalje, SE;
Inventors:
Karolina Nilsson, Sodertalje, SE;
Martin Bauer, Sodertalje, SE;
Maria Olwegard Halvarsson, Sodertalje, SE;
Mikael Brink, Sodertalje, SE;
Fredrik Bergström, Sodertalje, SE;
Assignee:
ASTRAZENECA AB, SÖDERTÄLJE, SE;
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 251/18 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 405/10 (2006.01); C07D 413/06 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 251/18 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 405/10 (2013.01); C07D 413/06 (2013.01); C07D 471/04 (2013.01); C07D 498/04 (2013.01);
Abstract
There are disclosed certain 2,4,6-trisubstituted 1,3,5-triazine compounds of Formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are modulators of CXCR1 and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disorders such as non-ischemic dilated cardiomyopathy and heart failure.