The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Mar. 24, 2023
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Michael E. Jung, Los Angeles, CA (US);

Xiaohong Chen, Los Angeles, CA (US);

Cun-Yu Wang, Los Angeles, CA (US);

Jiong Li, Van Nuys, CA (US);

Jie Zheng, Los Angeles, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/16 (2006.01); A61P 35/00 (2006.01); C07C 235/62 (2006.01); C07C 237/04 (2006.01); C07C 237/38 (2006.01); C07C 311/07 (2006.01); C07D 211/86 (2006.01); C07D 213/06 (2006.01); C07D 213/38 (2006.01); C07D 213/40 (2006.01); C07D 213/50 (2006.01); C07D 213/55 (2006.01); C07D 213/68 (2006.01); C07D 213/89 (2006.01); C07D 295/088 (2006.01); C07D 295/135 (2006.01); C07D 295/15 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01);
U.S. Cl.
CPC ...
C07D 213/68 (2013.01); A61P 35/00 (2018.01); C07C 235/62 (2013.01); C07C 237/04 (2013.01); C07C 237/38 (2013.01); C07C 311/07 (2013.01); C07D 211/86 (2013.01); C07D 213/06 (2013.01); C07D 213/38 (2013.01); C07D 213/40 (2013.01); C07D 213/50 (2013.01); C07D 213/55 (2013.01); C07D 213/89 (2013.01); C07D 295/088 (2013.01); C07D 295/135 (2013.01); C07D 295/15 (2013.01); C07D 295/16 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01);
Abstract

The present disclosure relates to compounds that are capable of modulating the WNT/Beta-Catenin pathway. The disclosure further relates to methods of treating colorectal cancer and other WNT/Beta-Catenin mediated cancers.


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