The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Mar. 08, 2023
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Assignee:
YALE UNIVERSITY, New Haven, CT (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/20 (2006.01); A61K 35/17 (2025.01); A61K 47/64 (2017.01); A61P 35/00 (2006.01); C07K 14/54 (2006.01); A61K 35/768 (2015.01); A61K 38/17 (2006.01); C07K 14/705 (2006.01); C12N 15/85 (2006.01);
U.S. Cl.
CPC ...
A61K 38/20 (2013.01); C07K 14/54 (2013.01); A61K 35/17 (2013.01); A61K 35/768 (2013.01); A61K 38/1774 (2013.01); A61K 47/642 (2017.08); A61K 2300/00 (2013.01); A61P 35/00 (2018.01); C07K 14/70596 (2013.01); C07K 2319/02 (2013.01); C07K 2319/21 (2013.01); C07K 2319/35 (2013.01); C07K 2319/50 (2013.01); C12N 15/85 (2013.01);
Abstract
The present invention provides compositions and methods comprising an activator of interleukin-18 (IL-18) activity for use in therapeutic and non-therapeutic applications. The activator provides IL-18 signaling activity even in the presence of an inhibitory molecule such as IL-18 binding protein (IL-18BP).