The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Feb. 18, 2022
Applicants:

The Board of Trustees of the University of Arkansas, Little Rock, AR (US);

National University Corporation Okayama University, Okayama, JP;

Inventors:

Joshua Sakon, Fayetteville, AR (US);

Robert Beitle, Fayetteville, AR (US);

Hazim Aljewari, Fayetteville, AR (US);

Osamu Matsushita, Okayama, JP;

Stephanie Beitle, Fayetteville, AR (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/17 (2006.01); A61K 38/18 (2006.01); A61L 31/10 (2006.01); A61L 31/16 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1825 (2013.01); A61K 38/164 (2013.01); A61K 38/1709 (2013.01); A61L 31/10 (2013.01); A61L 31/16 (2013.01);
Abstract

The present invention provides collagen-binding agents that can be used to treat wounds, ischemic heart disease, and other conditions. The collagen-binding agents comprise a therapeutic agent, a protease cleavage site, and a collagen-binding domain. The present invention further provides pharmaceutical compositions and biomedical devices comprising the disclosed collagen-binding agents, as well as methods for treating a condition using the collagen-binding agents.


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