The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 02, 2025

Filed:

Sep. 27, 2021
Applicant:

Ocean University of China, Shandong, CN;

Inventors:

Changyun Wang, Shandong, CN;

Changlun Shao, Shandong, CN;

Mengqi Zhang, Shandong, CN;

Hong Bai, Shandong, CN;

Xia Ren, Shandong, CN;

Shijun Yue, Shandong, CN;

Lanting Xin, Shandong, CN;

Qing Zhao, Shandong, CN;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 36/19 (2006.01); A61K 31/192 (2006.01); A61K 31/7032 (2006.01); A61P 1/16 (2006.01);
U.S. Cl.
CPC ...
A61K 36/19 (2013.01); A61K 31/192 (2013.01); A61K 31/7032 (2013.01); A61P 1/16 (2018.01); A61K 2236/15 (2013.01); A61K 2236/17 (2013.01); A61K 2236/333 (2013.01); A61K 2236/51 (2013.01);
Abstract

Provided are a phenylethanoid glycoside extract from the plantL., a preparation method thereof, and its use as an anti-liver injury medicament. The preparation method of the phenylethanoid glycoside extract comprises following steps: pulverizing dried whole plantL. and passing through 20-30 mesh sieve to obtainL. powder, adding 50%-95% ethanol solution whose mass is 8-20 times of the powder, soaking and extracting under reflux, filtering and collecting extract of the powder, and extracting a filter residue under reflux with 50%-95% ethanol solution whose mass is 8-10 times of the filter residue and collecting extract of the filter residue, combining, concentrating and subjecting to macroporous resin column chromatography, eluting successively by 10%, 30% and 50% ethanol solutions for four column volumes, respectively, collecting fraction eluted by the 50% ethanol solution and drying to obtain the phenylethanoid glycoside extract.


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