The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Jul. 09, 2020
Applicant:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Inventors:
Eric Scott Lightcap, Somerville, MA (US);
Yosuke Sato, Osaka, JP;
Assignee:
Takeda Pharmaceutical Company Limited, Osaka, JP;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/7084 (2006.01); A61K 35/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7084 (2013.01); A61K 35/00 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure provides methods, pharmaceutical compositions, and kits for treating cancer in patients in need thereof. The methods comprise administering to a patient in need a STING (stimulator of interferon genes) agonist, such as Compound No. 14, or a pharmaceutically acceptable salt thereof, in combination with one or more checkpoint inhibitors. Suitable checkpoint inhibitors include anti-PD-1 antibodies, anti-PD-L1 antibodies and anti-CTLA-4 antibodies. Also provided are medicaments for use in treating cancer. Compound No. 14 has the structure: