The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Jun. 03, 2020
Ifom Fondazione Istituto Firc Di Oncologia Molecolare, Milan, IT;
Ieo—istituto Europeo Di Oncologia S.r.l., Milan, IT;
Sebastiano Pasqualato, Milan, IT;
Maurizio Pasi, Torre d'Isola, IT;
Raffaella Amici, Codogno, IT;
Mario Varasi, Milan, IT;
Ciro Mercurio, Legnano, IT;
Luca Sartori, Milan, IT;
Simona Polo, Milan, IT;
Elena Maspero, Milan, IT;
Giovanni Faga', Milan, IT;
IFOM —FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE, Milan, IT;
IEO—ISTITUTO EUROPEO DI ONCOLOGIA S.R.L., Milan, IT;
Abstract
The present invention relates to tricyclic derivatives of formula (I), which are useful as inhibitors of HECT-domain-containing E3 ligases, in particular NEDD4. The present invention also refers to pharmaceutical compositions comprising compounds of formula (I), to their medical use and to their process of preparation.