The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2025
Filed:
Jul. 31, 2020
Applicant:
Aclaris Therapeutics, Inc., Wayne, PA (US);
Inventors:
David Randolph Anderson, Salem, CT (US);
Gary Anthony Decrescenzo, Parkville, MO (US);
Assignee:
Aclaris Therapeutics, Inc., Wayne, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/506 (2013.01); A61P 35/00 (2018.01); A61P 37/02 (2018.01); C07D 401/14 (2013.01);
Abstract
The present disclosure provides deuterated pyridinone-pyridinyl compounds and compositions useful in the treatment of p38 MAP Kinase mediated having the structures of Formula (I); wherein the A, B, and R groups are as defined in the detailed description. Methods of inhibition of p38 MAP Kinase activity in a human or animal subject are also provided.