The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Oct. 09, 2019
Applicant:

Celgene Corporation, Summit, NJ (US);

Inventors:

Yixin Wang, Basking Ridge, NJ (US);

Sarah Hersey, Mendham, NJ (US);

Fadi George Towfic, Madison, NJ (US);

Alberto Risueno Perez, Seville, ES;

Assignee:

CELGENE CORPORATION, Summit, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G16B 20/30 (2019.01); G01N 33/574 (2006.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01);
U.S. Cl.
CPC ...
G16B 20/30 (2019.02); G01N 33/57407 (2013.01); G16H 50/20 (2018.01); G16H 50/30 (2018.01); G01N 2333/47 (2013.01); G01N 2333/70596 (2013.01); G01N 2333/71 (2013.01);
Abstract

A method of predicting if a subject has an Activated B Cell-like (ABC) subtype or a non-ABC subtype of Diffuse Large B-Cell Lymphoma (DLBCL), comprising (a) obtaining a sample from the subject; (b) measuring the expression levels of CD10, MUM1, FOXP1, and optionally Bcl-6; (c) determining a composite score based on the expression levels of CD10, MUM1, and FOXP1, and optionally Bcl-6; and (d) predicting if the subject has an ABC subtype or a non-ABC subtype of DLBCL based on the composite score.


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