The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Apr. 07, 2022
Applicant:

University of Rhode Island Board of Trustees, Kingston, RI (US);

Inventors:

Jimmie Oxley, Narragansett, RI (US);

James L. Smith, Narragansett, RI (US);

Alexander Yevdokimov, Norwich, CT (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/00 (2006.01); G01N 27/622 (2021.01); H01J 49/00 (2006.01); H01J 49/26 (2006.01);
U.S. Cl.
CPC ...
G01N 27/622 (2013.01); H01J 49/0031 (2013.01); H01J 49/26 (2013.01);
Abstract

The present disclosure describes an improved sample preparation technique, swab, swab holder and solvent for the removal of trace chemical materials from swabs and delivery of the trace materials into a mass spectrometer (MS) or an ion mobility spectrometer (IMS). The devices and techniques aid the delivery of the analyte into the instrument inlet and concurrently serves as an ionization source. The technique includes the steps of positioning or shaping the swab so that a pointed analyte release area is directed toward the inlet of the MS or IMS, adding a solvent to the swab and charging the swab to create an ionized analyte spray (Taylor Cone spray) into the inlet of the detection instrument. Solvent may include a chemical for depressing the ionization of residual solvent or enhancing the ionization of the desired analyte and this chemical may serve as an internal standard or benchmark.


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