The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 26, 2025
Filed:
Jun. 03, 2022
Purdue Research Foundation, West Lafayette, IN (US);
Genentech, Inc., South San Francisco, CA (US);
Andrew Strongrich, West Lafayette, IN (US);
Alina Alexeenko, West Lafayette, IN (US);
Fredric John Lim, Fremont, CA (US);
Lokesh Kumar, San Mateo, CA (US);
Purdue Research Foundation, West Lafayette, IN (US);
Genentech, Inc., South San Francisco, CA (US);
Abstract
A lyophilization method for lyophilizing products inside one or more vials within a lyophilization chamber is disclosed which includes humidifying a charge gas to a predetermined relative humidity, cooling shelves in the lyophilization chamber to a predetermined temperature, pressurizing the chamber with the humidified charge gas to a pressurization threshold to thereby achieving a target relative humidity level within the lyophilization chamber, and suddenly releasing pressure within the lyophilization chamber until a depressurization threshold is reached in a short time interval up to about 4 seconds, during the depressurization, product inside one or more vials nucleate.