The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Mar. 30, 2023
Applicant:

Duke University, Durham, NC (US);

Inventors:

Bruce Sullenger, Durham, NC (US);

Bethany Gray, Durham, NC (US);

Michael Nichols, Durham, NC (US);

Assignee:

DUKE UNIVERSITY, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); C12N 5/09 (2010.01); C12Q 1/6881 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6881 (2013.01); C12N 5/0693 (2013.01); C12N 15/115 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3517 (2013.01);
Abstract

Provided herein are compositions and methods for sorting and/or identifying live cells. The compositions and methods provide for staining of live cells with aptamer so particular cells can be identified within or sorted from a heterogeneous population of live cells and subsequent reversal of the staining to prepare sorted and/or identified cells in their native state.


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