The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Jul. 12, 2023
Applicant:

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Sherry L. Voytik-Harbin, Zionsville, IN (US);

Stacey L. Halum, Indianapolis, IN (US);

Sarah Brookes, West Lafayette, IN (US);

Hongji Zhang, Naperville, IL (US);

Assignee:

Purdue Research Foundation, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C12N 5/00 (2006.01); C12N 5/074 (2010.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0068 (2013.01); C07K 14/78 (2013.01); C12N 5/0062 (2013.01); C12N 5/0652 (2013.01); C12N 5/0696 (2013.01); C12N 2500/34 (2013.01); C12N 2533/54 (2013.01);
Abstract

The present disclosure provides solid collagen constructs and tissue compositions, wherein a polymerizable collagen solution or suspension is extruded in the presence or absence of cells to formed an aligned architecture comprising solid collagen constructs such as those made with fibrillar collagen. Methods of using and of manufacturing solid collagen constructs and tissue compositions, where the component collagen is solid fibrillar collagen and cells are preferentially aligned, are also provided.


Find Patent Forward Citations

Loading…