The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2025

Filed:

Jul. 30, 2020
Applicant:

Elanco Us Inc., Greenfield, IN (US);

Inventors:

Hangjun Zhan, Foster City, CA (US);

Lam Nguyen, Union City, CA (US);

Ellen Ratcliff, Burlingame, CA (US);

Richard Chin, San Francisco, CA (US);

Shyr Jiann Li, Millbrae, CA (US);

Assignee:

Elanco US Inc., Greenfield, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/08 (2006.01); A61P 31/20 (2006.01);
U.S. Cl.
CPC ...
C07K 16/081 (2013.01); A61P 31/20 (2018.01); C07K 2317/24 (2013.01); C07K 2317/515 (2013.01); C07K 2317/52 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract

Provided are various embodiments relating to parvovirus antibodies, including caninized, felinized, and chimeric antibodies, that bind to canine and/or feline parvovirus, for example, having improved expression characteristics. In various embodiments, the parvovirus antibodies have ADCC, ADCP, and/or CDC effector functions. In various embodiments, such monoclonal parvovirus antibodies can be used in methods to prevent and/or treat parvoviral infection in subjects, such as dogs and cats. For example, the parvovirus antibodies provided may be used to provide passive immunity against infection with a canine or feline parvovirus.


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